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Research Applications of Developmental Biology


Admission requirements


Period: 14 June 2021 - 2 July 2021

Many research fields are founded in the field of Developmental Biology. One can think of for example basic research into signaling pathways, as pathological signaling often hijacks embryonic pathways, but also towards clinical research into the field of congenital anomalies. Embryos of various species, like mice, chicken, and zebrafish, are often used to investigate genetic, physiological or pharmacological influences on organogenesis or disease progression. And of course there is the growing field of stem cell research which ranges from basic research to clinical applications by using embryonic stem cells, mesenchymal stem cells, or induced pluripotent stem cells.

In this course the abovementioned aspects will be covered, often with a focus on cardiovascular development. Topics will vary slightly from year to year. The following topics have been addressed previously:
1. Embryonic signaling as blueprint for cardiac pathology.
2. Embryo models for cardiovascular research.
3. Stem cells in cardiovascular disease models, organ on a chip.
4. Early embryogenesis and fertility.

The course design will be based on the TeamBased Learning (TBL) concept. This means that learning is a combination of individual and team effort, and that the learning outcomes will be partly determined by the teams. This concept requires fulltime attendance during the course. The subjects will be discussed and presented successively in blocks of 3-4 days which will each consist of an orientation, testing, meet-the-expert, problem solving, and a presentation phase. Details about this learning method will be provided on day 1.

This course will particularly work on:
Research competences:
Professional competences:

Course objectives

The student:

  • knows and shows insight in relevant biomedical knowledge such as: embryonic signaling as blueprint for pathology, embryo models for cardiovascular research, stem cells in disease models, organ on a chip, germ cells and fertility

  • is able to treat or solve a problem or issue using scientific rules, methods and thinking

  • applies biomedical knowledge adequately such as : embryonic signaling as blueprint for pathology, embryo models for cardiovascular research, stem cells in disease models, organ on a chip, germ cells and fertility in order to solve a specific research problem in the developmental biology field

  • substantiates arguments in a well-balanced yet clear way

  • shows communication skills in order to write and present coherently and convincingly while taking into account modern presentation and writing principles

  • is able to acquire and extend knowledge and understanding independently and efficiently and in doing so reflecting on own actions in order to improve his/her own product or approach

  • cooperates constructively with peers and in doing so assessing work of others when give some basic criteria in a valid and realistic way and give and receive peer feedback constructively

  • is able and aware of the necessity to keep abreast of relevant developments in the biomedical field, and to assess where his/her own research can contribute to the field


All course and group schedules are published on our LUMC scheduling website or on the LUMC scheduling app.

Mode of instruction

Assessment method

Summative assessment:

  • Written exams (individual exam and team exam with possibility for an appeal on the exam questions).

  • Interview with expert

  • Peer assessment

Reading list

Will be distributed during the course.


Registration for FOS courses, H2W, Scientific Conduct, How to start, Course on Animal Science , and CRiP and Adv concepts courses takes place in lottery rounds in the beginning of July. After the lottery rounds: if you want to register for a course you are kindly asked to contact the student administration at