Core course in MSc Life Science and Technology (Biophysical Sciences series), MSc Chemistry elective.
For students with a BSc in MST, LST, BFW or equivalent. Students are expected to have a basic understanding of (in)organic chemistry and/or cell biology.
This course introduces the field of biomaterials science, a rapidly growing area at the interface between chemistry, materials science and biology. Throughout the course, the potential of hard (e.g. metals, ceramics) and soft materials (e.g. polymers, hydrogels, liposomes) to specifically modulate various biological processes will be explored at several length scales in the context of wound healing, regeneration and disease. Moreover, an in-depth evaluation of the preparation methods of various materials scaffolds and their characterization will also be presented. The overall goal of this course is for students to gain an appreciation of the impressive developments and challenges faced in this interdisciplinary field, but also to grasp the opportunities for the intervention of materials at the biological interface.
For more information on the topic, see supramolecular materials: from biosensors to cell delivery devices
At the end of the course the students
will have an overview of the field of biomaterials science.
will be able to explain the preparation and characterization of a range of hard and soft biomaterials using various physical and chemical techniques as well as an understanding of the cellular responses to them from the molecular to the macroscopic scales.
will be able to describe the strategies used to prepare implants composed of metal-based alloys and bioceramics, their characterization and applications in load-bearing tissues.
will be able to explain fundamental aspects of polymers and their characterization as materials (e.g. hydrogels) and methods to enable their interfacing with biological matter.
will be able to compare delivery strategies in the fields of macroscale and particulate drug delivery from the preparation of the scaffolds to their application.
will be able to summarize the use of biomaterials in rapidly developing areas such as tissue engineering, regenerative medicine, bioprinting, and immunoengineering.
will be able to apply the knowledge gained during the course to critique and present a basic research article in the biomaterials area and to follow a presentation from a researcher in the field.
Schedule information can be found on the website of the programmes. Assignment deadlines are communicated via Brightspace.
Mode of Instruction
The course consists of weekly lectures, guest lectures and student presentations.
Literature assessment (40%) and a written exam (60%)
Selected research articles and reviews that will help to guide the lecture material will be provided via Brightspace
Register for this course via uSis
Dr. Roxanne Kieltyka, Prof.dr. Alexander Kros
According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.