Core course in MSc Chemistry – Energy and Sustainability, elective course in MSc Chemistry
Students with a BSc degree in MST with a major in Chemistry or a BSc degree in Chemistry. Other candidates should have a solid background in coordination chemistry, including understanding of sigma and pi donation, pi back-donation, electron count of transition metal compounds, 18 and 16 electron rule.
The course starts with the fundamental principles of coordination and organometallic chemistry: electron counting, stability and reactivity, reaction mechanisms, steric and electronic influence of the ligands on reactivity of the metal centers. In the second part of the course this knowledge will be used in the discussion of various homogeneously catalysed reactions, notably double bond isomerisation, (enantioselective) hydrogenation, hydroformylation, hydrocarboxylation, oligo- and polymerisation and alkene methathesis. In the lectures attention will be given to the applications of homogeneous catalysis in industrial processes and academic research.
At the end of the course students:
will have knowledge of fundamental principles of organometallic chemistry
will have knowledge of the fundamental principles of homogeneous catalysis
will have knowledge of the principles of atom-efficiency and sustainable chemistry
will be able to construct a mechanism of various homogeneously catalysed reactions.
will be able to construct tentative catalytic mechanisms also for reactions that were not discussed
Mode of instruction
Lectures and exercises
Schedule information can be found on the website of the programmes.
The course is based on the following book: R.H. Crabtree, The Organometallic Chemistry of the Transition Metals, Wiley Interscience (5th Ed: ISBN: 978-0-470-25762-3, or 6th Ed: ISBN: 978-1-118-13807-6). Slides presented during the courses Excercises
Written examination (100%)