Core course in MSc Life Science and Technology
Chemical genetics is a research method that uses small molecules to change the way proteins work- directly in real time rather than indirectly by manipulating their genes. It is used to identify which proteins regulate different biological processes, to understand in molecular detail how proteins perform their biological functions, and to identify small molecules that may be of medical value.
In this course several examples of chemical genetics will be introduced. The biology of the problems will be introduced by a molecular geneticist (Prof. Jaap Brouwer) and subsequently the chemistry will be explained by chemical specialists (Dr. Bobby Florea, Dr. Sylvestre Bonnet, Dr. Roxanne Kieltyka, Dr. Sander van Kasteren and Dr. Rolf Boot).
Presence at classes is obligatory.
Open book exam