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Biomedical Translational Research in Surgery


Admission requirements

The course will be given at level 500, expanding on knowledge acquired in the first- and second-year Bachelor-s courses.


Period: April 2 – April 20, 2012

Content of the course

The main theme of this advanced course is a translational biomedical research in surgery. Based on examples from the current research program in the department of surgery, the students will be introduced in the translational aspects of the biomedical research currently being performed in the deparment. This comprises the vascular surgery research focused on vascular remodeling in aneurysm formation, atherosclerosis and angiogenesis, the surgical oncology research on biomarkers, proteomics in various tumors as well as image guided surgery, and touches upon trauma surgery research, both epidemiological and biomedical.
The close interaction between clinic and basic research will be addressed by presenting topics both from a clinical point of view by clinicians and from a basic research point of view by the reseachers, illustrating the interactions in the program.
The course consists of lectures, assignments and lectures prepared by the students. Practical aspects that are addressed comprise a TNA analysis as usually is performed in out group.


The first week will consist of an introduction in the vascular research program, starting with the assignments and preparing the first group lectures, the second week will mainly be focused on oncological surgery and its research aspects and the last week will be mainly focused on the assignments and the student presentations.

This course will particularly work on:

Research competences:
Addressing a clinical problem in a translational way, integrating clinical and basic research aspects. This in being done both by preparing presentations on relevant topics and designing adequate research programs on selected topics.

Professional competences:
Collaborating with peers, apprehending new information on clinical issues, combined with basic research issues on that very topic and translate this new knowledge in practical research proposals.

Course objectives

The student will obtain a broader and deeper insight into:

  • several topics of translational scientific research within the department of Surgery of the LUMC.

  • how current challenges in clinics can be translated into research projects with a more biomedical character.
    The student is able to:

  • to formulate a research question and present a possible approach for addressing this in a research project

Mode of instruction

Plenary seminars provided by experts in the field, self study assignments and interactive discussion s between trainees and tutors, presentations prepared by students (assisted by tutors) and practical work in the form TMA analysis.

Assessment method

Overall assessment is based on the quality of the oral presentation and defense of a assignments, the group lectures, and the overall student behaviour during the course (motivation, independency, oral reporting, participation in work and scientific discussions).