nl en

In-vivo biomolecular interactions underlying diseases (IBID)


Admission requirements

Core course in MSc Life Science and Technology, elective course MSc Chemistry.
For students with a BSc LST or equivalent, or for students who have passed Molecular Cell Biology (4423MOLCB) after 2020 or Cell Biology (4423CELBI) and Molecular Biology (4423MOLBI) in earlier years.


Studies of in-vivo bio-molecular interactions are essential for our understanding of cellular functioning. Specific in-vivo interactions controlling different aspects of cellular function and physiology will be discussed in normal, healthy and disease-related, situations. A strong emphasis will also lie on chemical biology aspects of lysosomal storage diseases. Academic skills of writing, reading scientific articles and giving presentations are included.

Course objectives

At the end of the course students:

  • Will have in depth understanding of fundamental cell and molecular biology aspects of normal cell situations.

  • Will have in depth knowledge of fundamental principles of bio-molecular interactions underlying diseases and understanding of drug target finding relevant for developing novel drugs

  • Will have knowledge of the societal impact of cell biology for curing world-wide threatening diseases, such as lysosomal storage and other neurological diseases.

  • Can digest a scientific article from the literature, including details on how to perform research in relation to molecular pathways.

  • Will be able to write scientific mini-reviews based on recent cell biology/disease literature.

  • Will be able to present orally recent cell-biology/disease related literature

  • Will be able to understand the current disease-related cell biology literature that was not discussed


Schedule information can be found on the website of the programmes.

You will find the timetables for all courses and degree programmes of Leiden University in the tool MyTimetable (login). Any teaching activities that you have sucessfully registered for in MyStudyMap will automatically be displayed in MyTimeTable. Any timetables that you add manually, will be saved and automatically displayed the next time you sign in.

MyTimetable allows you to integrate your timetable with your calendar apps such as Outlook, Google Calendar, Apple Calendar and other calendar apps on your smartphone. Any timetable changes will be automatically synced with your calendar. If you wish, you can also receive an email notification of the change. You can turn notifications on in ‘Settings’ (after login).

For more information, watch the video or go the the 'help-page' in MyTimetable. Please note: Joint Degree students Leiden/Delft have to merge their two different timetables into one. This video explains how to do this.

Mode of instruction

Lectures and instructions in scientific writing

Assessment method

Writing scientific essays (70%) and an oral presentation (30%)

Reading list

The course is based on recent articles, either review or research papers relevant for modern cell biology/molecular disease studies and papers of on-going related research in the LIC and in cooperating institutes
Slides presented during the courses


From the academic year 2022-2023 on every student has to register for courses with the new enrollment tool MyStudyMap. There are two registration periods per year: registration for the fall semester opens in July and registration for the spring semester opens in December. Please see this page for more information.

Please note that it is compulsory to both preregister and confirm your participation for every exam and retake. Not being registered for a course means that you are not allowed to participate in the final exam of the course. Confirming your exam participation is possible until ten days before the exam.

Extensive FAQ's on MyStudymap can be found here.


Dr. Rolf Boot


Assignment deadlines are communicated via Brightspace.

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.