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Supramolecular Chemistry (SUP)


Admission requirements

Core course in MSc Chemistry - Chemical Biology, elective course in MSc Chemistry and MSc Life Science and Technology
For students with a BSc in MST, LST or equivalent. Students with a BSc in physics should have a solid background in synthetic and/or physical-organic chemistry. Students are expected to have a basic understanding of non-covalent interactions, standard organic reactions and relevant characterization techniques, notably NMR, UV, fluorescence, and IR spectroscopy.


This course provides an introduction to the field of supramolecular chemistry. By using case studies, the interplay of various non-covalent interactions in addition to concepts such as multivalency, preorganization, complementarity and self-assembly will be explored with respect to various classes of supramolecular structures. Additionally, a special focus will be dedicated on the characterization of supramolecular assemblies from the molecular to the macroscales. Various subdisciplines and potential applications within the field of supramolecular chemistry will be discussed (e.g. functional assemblies like molecular machines, sensors, drug delivery, biomaterials for regenerative medicine).

Course objectives

At the end of the course students:

  • will have knowledge of fundamental principles of supramolecular chemistry

  • will have in-depth knowledge of non-covalent interactions

  • will have an overview of the areas of supramolecular polymers, nucleic acid nanotechnology,

  • will be able to understand the design principles behind a range of supramolecular constructs and propose new supramolecular designs and functions.

  • can digest and present a critical summary of a scientific article from the literature


Schedule information can be found on the website of the programmes.

You will find the timetables for all courses and degree programmes of Leiden University in the tool MyTimetable (login). Any teaching activities that you have sucessfully registered for in MyStudyMap will automatically be displayed in MyTimeTable. Any timetables that you add manually, will be saved and automatically displayed the next time you sign in.

MyTimetable allows you to integrate your timetable with your calendar apps such as Outlook, Google Calendar, Apple Calendar and other calendar apps on your smartphone. Any timetable changes will be automatically synced with your calendar. If you wish, you can also receive an email notification of the change. You can turn notifications on in ‘Settings’ (after login).

For more information, watch the video or go the the 'help-page' in MyTimetable. Please note: Joint Degree students Leiden/Delft have to merge their two different timetables into one. This video explains how to do this.

Mode of instruction

Lectures and student presentations of a supramolecular chemistry article.

Assessment method

Written article review and on-campus presentation (30%) and a written exam (70%).

Reading list

Supramolecular Chemistry, 3rd Edition, by Jonathan W. Steed, Jerry L. Atwood ISBN: 978-1-119-58251-9 February 2022
Recent literature (review and research papers) will be provided during the course


From the academic year 2022-2023 on every student has to register for courses with the new enrollment tool MyStudyMap. There are two registration periods per year: registration for the fall semester opens in July and registration for the spring semester opens in December. Please see this page for more information.

Please note that it is compulsory to both preregister and confirm your participation for every exam and retake. Not being registered for a course means that you are not allowed to participate in the final exam of the course. Confirming your exam participation is possible until ten days before the exam.

Extensive FAQ's on MyStudymap can be found here.


Prof.dr. Alexander Kros, Dr. Roxanne Kieltyka and Dr. Sander Wezenberg. Group website


Assignment deadlines are communicated via Brightspace.

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.