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Single Molecule Optics



In SMO we discuss the experimental methods for, and the main results of, the optical study of isolated molecules, nanocrystals and nanoparticles. The lectures scan a wide range of techniques and phenomena including fluid solutions, solid samples at room temperature, and low-temperature experiments with extremely high spectral resolution. The course is an opportunity to apply many concepts of molecular physics, statistical physics, solid state physics and plasmonics. Topics:

  • Fluorescence spectroscopy

  • Optical microscopy and resolution limits

  • Correlation spectroscopy in fluid solutions

  • Fluorescence resonance energy transfer

  • High-resolution spectroscopy

  • Interacting single molecules

  • Semiconductor nanocrystals

  • Plasmonic nanoparticles

Programme form

Lectures only


Syllabus and literature articles


Physics Schedule

Form of examination

Oral examination at the end of the course


Classical and quantum physics until Bachelor level. Atomic and Molecular Physics is very useful, but not required.

More information

Lecturer: Prof.dr. M. Orrit (Michel)