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Quantitative Pharmacology


Admission requirements

Students of Bio-Pharmaceutical Sciences. Adequate knowledge of Pharmacology and Statistics.


This lecture series comprises the theoretical basis and application of quantitative pharmacology and pharmacokinetic-pharmacodynamic (PK-PD) modeling with the purpose of characterizing and predicting the onset, intensity, and duration of drug effects in patients.

Course objectives

  • obtain understanding of the most commonly used types of quantitative modeling approaches in pharmacology;

  • learn how to choose the most relevant quantitative modeling strategy to address a particular pharmacological question given the availability of prior knowledge or data;

  • develop an ability to understand and critically review quantitative modeling reports (e.g., publications);

  • obtain basic understanding in conducting common quantitative model-based analyses;

  • obtain understanding of the principles and analysis of differential equations in pharmacology.


The course is taught in March/April 2021. The specific schedule will be published on Brightspace.

Mode of instruction

The course will mainly consist of lectures and hands-on exercises. Active participation in the discussions and self-study skills are required for this course.

Assessment method

Written Exam (75%), and assignments (25%). The minimum average grade to pass this course is 6 out of 10.

Reading list

Will be announced during the course.


Application via uSis. Registration closes 14 days before the start of the course.


Coordinator: Dr. J.G.C. van Hasselt (coen.vanhasselt@lacdr.leidenuniv.nl)


A minimum of 5 participants is required, with a maximum of 25 students. Placement is based on the registration date.

This information is without prejudice. Alterations can be made for next year