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Supramolecular Chemistry (SUP)


Admission requirements

Core course in MSc Chemistry - Chemical Biology, elective course in MSc Chemistry and MSc Life Science and Technology
For students with a BSc in MST, LST or equivalent. Students with a BSc in physics should have a solid background in synthetic and/or physical-organic chemistry. Students are expected to have a basic understanding of non-covalent interactions, standard organic reactions and relevant characterization techniques, notably NMR, UV, fluorescence, and IR spectroscopy.


This course provides an introduction to the field of supramolecular chemistry. A primer on non-covalent interactions will be provided. By using case studies, the interplay of various non-covalent interactions in addition to concepts such as multivalency, preorganization, complementarity and self-assembly will be explored with respect to various classes of supramolecular structures. Additionally, a special focus will be dedicated on the characterization of supramolecular assemblies from the molecular to the macroscales. Various subdisciplines and potential applications within the field of supramolecular chemistry will be discussed (e.g. functional assemblies like molecular machines, sensors, drug delivery, biomaterials for regenerative medicine)

Course objectives

At the end of the course students:

  • will have knowledge of fundamental principles of supramolecular chemistry

  • will have in-depth knowledge of non-covalent interactions

  • will have an overview of the areas of supramolecular polymers, nucleic acid nanotechnology,

  • will be able to understand the design principles behind a range of supramolecular constructs and propose new supramolecular designs and functions.

  • can digest and present a critical summary of a scientific article from the literature


Schedule information can be found on the website of the programmes. Assignment deadlines are communicated via Brightspace.

Mode of instruction

Lectures and student presentations of a possible supramolecular chemistry project

Assessment method

Article review (30%)
Written exam (70%)

Reading list

Recent literature (review and research papers) will be provided during the course


Register for this course via uSis


Prof.dr. Alexander Kros, Dr. Roxanne Kieltyka and Dr. Sander Wezenberg. Group website


According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.