Molecular Chemistry is a core course for MSc LST students. Note: this course is not intended for master students that did finish a BSc MST !
Fundamental concepts of organic chemistry, such as acidity/basicity, orbital interactions, conjugation, etc. are discussed. The most common transformations and corresponding mechanisms are explained and illustrated with examples of reactions that are used in the total synthesis of natural compounds or are part of biological processes. The lecture series includes interactive discussions and problem solving sessions.
After the course the student is able to:
Apply the fundamental concepts of organic chemistry in the analysis and construction of molecules
Construct the mechanism of a reaction in terms of electron movement and/or participating orbitals
Predict the structures of products for the most common organic reactions
Provide one or more critical arguments which reagents and conditions are more suitable than others based on the knowledge of the structure and reactivity of the molecules
Design a synthesis of a small molecule based on identification of structural functionalities
Identify key components in a chemical reaction which you can use to explain the regio- and stereoselectivity of that reaction
Organic Chemistry, 2nd edition, Clayden, Greeves and Warren
Written exam (“closed book”)
Basic knowledge of organic chemistry (BSc in Life Science and Technology or a related discipline).
About the lecturers
Stefan van der Vorm
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