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Synthetic Organic Chemistry (SOC)

Vak
2018-2019

Admission requirements

BSc MST students with a major in Chemistry, BSc LST students.

Description

Strategies for the synthesis of current of newly developed drugs are discussed, including retro-synthetic analysis, introduction and modification of functional groups and the use of protective groups, control of stereo- and regio-selectivity.

Course Objectives

After the course students:

  • Will have knowledge of the relation of structure and reactivity of organic molecules;

  • Will have knowledge of standard chemical reactions, with a focus on functional group conversions;

  • Will have knowledge of chemical concepts such as delocalization, conjugation, stereochemistry, tautomerism, regio-, chemo- and stereoselectivity, and aromaticity.

  • Will be able to apply the chemical concepts;

  • Will be able to predict the structures of products of standard reactions;

  • Will be able to predict the required reagents for standard reactions;

  • Will be able to describe the mechanism of reactions.

Reading list

  • Organic chemistry, Clayden, Greeves, Warren, Oxford University

  • Literature will be provided during the course.

Coordinator

Dhr. Prof. Dr. G.J. van der Marel

Mode of instruction

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Lectures with active participation of the student

Assessment method

Written exam

Registration

Register for this course via Usis.