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Solid State NMR (SSNMR)


Admission requirements

Elective course MSc Chemistry, MSc LST for students with a BSc in LST, MST, Physics or equivalent.


Theoretical basis of modern Solid State NMR-spectroscopy, non-stationary processes. Introduction into coherent spin dynamics and solid state NMR for materials, and biomolecules.
The basis is the density matrix formalism for non-stationary processes in the solid state, and how to manipulate the dynamics in spin space and real space with a spectrometer, exploring the symmetry of the theoretical description. During the course we will perform computer simulations of NMR experiments for gaining hands-on experience, and there is room for the students bringing in their own favorite pulse sequences for analysis.

Course objectives

At the end of the course students:

  • Will have the analytical skills to mathematically manipulate quantum coherent dynamics with operators, rotations and average Hamiltonian theory

  • Will have the skill to do computer simulations like quantum propagators of 1-D and 2-D NMR pulse sequences; localized spectroscopy depending on the students’ interest

  • Will have the skill of transfer of knowledge: apply principles of coherent dynamics and product to quantum chemistry and quantum biology

  • Will be able to see the density matrix and propagator formalism

  • Will be introduced into the logic of analyzing coherent dynamics in the product of quantum and real space

  • Will be able, after installing the Simpson virtual spectrometer on their own laptop, to simulate their NMR experiments

  • Will gain knowledge about the transfer to quantum chemistry and quantum biology


Schedule information can be found on the website of the programmes.

You will find the timetables for all courses and degree programmes of Leiden University in the tool MyTimetable (login). Any teaching activities that you have sucessfully registered for in MyStudyMap will automatically be displayed in MyTimeTable. Any timetables that you add manually, will be saved and automatically displayed the next time you sign in.

MyTimetable allows you to integrate your timetable with your calendar apps such as Outlook, Google Calendar, Apple Calendar and other calendar apps on your smartphone. Any timetable changes will be automatically synced with your calendar. If you wish, you can also receive an email notification of the change. You can turn notifications on in ‘Settings’ (after login).

For more information, watch the video or go the the 'help-page' in MyTimetable. Please note: Joint Degree students Leiden/Delft have to merge their two different timetables into one. This video explains how to do this.

Mode of instruction

Lectures. This is an interactive course with a high level of participation from the students with peer-instruction.

Assessment method

The grade assessment for this course consists of three parts:

  • In-class participation in the peer instruction: 40%

  • Simulation of pulse sequences exercises, reports to be handed in: 30%

  • Multiple choice quantitative literacy test: 30%

Reading list

Compulsory reading: M.J. Duer, “Solid State NMR spectroscopy”


From the academic year 2022-2023 on every student has to register for courses with the new enrollment tool MyStudyMap. There are two registration periods per year: registration for the fall semester opens in July and registration for the spring semester opens in December. Please see this page for more information.

Please note that it is compulsory to both preregister and confirm your participation for every exam and retake. Not being registered for a course means that you are not allowed to participate in the final exam of the course. Confirming your exam participation is possible until ten days before the exam.

Extensive FAQ's on MyStudymap can be found here.


Prof.dr. Huub de Groot


This biennial course will not be given in 2022-23. Shown above is the course description for 2020-21 as reference. The course is scheduled again for academic year 2023-24.

Assignment deadlines are communicated via Brightspace.

According to OER article 4.8, students are entitled to view their marked examination for a period of 30 days following the publication of the results of a written examination. Students should contact the lecturer to make an appointment for such an inspection session.