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Metabolomics

Vak
2020-2021

Admission requirements

Advice: Participants should have basic knowledge of Systems Biology, Natural Products or a similar course. There is limited space for students in this course. You have to register in usis for this course. In February 2020 we will contact the students who are registered whether they can follow the course.

Contact

Coordinator: Dr. Y. H. Choi Email: y.choi@chem.leidenuniv.nl

Description

Metabolomics has become an important metabolic profiling tool in life sciences, including studies of plant interaction with its environment and studies on the activity of medicinal plants. This course will cover basic phytochemistry, analytical platforms for metabolomics (NMR, Chromatography, Mass Spectrometry), data interpretation with Multivariate Data Analysis, and example of application of metabolomics to life science.

Learning goals

Course objectives: This course aims at providing broad knowledge on the metabolomics. Participants are expected to learn about basic biosynthesis of natural products, analytical chemistry of natural products using chromatography and spectroscopy, and data mining with a series of multivariate data analysis.

Final qualifications: Participants understand the goal of metabolomics in life science, basic concept of analytical platforms (chromatography, Mass spectrometry, and NMR) currently used for metabolomics. Also, they will understand the basics of multivariate data analysis to interpret analytical data.

Timetable

From 29 March 2021 to 16 April 2021, see Brightspace for detailed timetable.

1 week for theory, 1 week for practice, 1 week for wrap-up course for structure elucidation, 1 week for self-study, exam.

Mode of instruction

Lectures, practice, reading of articles

Assessment method

Written examination

The final grade is soley based on:

  • Written exam, to cover theory (1st week)

  • Practicum (2nd week)

  • Wrap-up (3rd week)

The minimum grade is 6 out of 10.

Inspection and feedback on the examination

Date: 16/04/2021

Brightspace

Brightspace is used for communication and for course material

Reading list

Basic reading list will be provided 3 months before the course

Registration

Registration deadline: Before 31 January 2021 There is limited space for students in this course. You have to register in usis for this course. In February 2021 will we contact the students who are registered whether they can follow the course.

Via Usis

Exchange and Study Abroad students, please see the Prospective students website for more information on how to apply.

Remarks

This course is a part of an international workshop (Metabolomics Workshop) organized by Y.H. Choi and R. Verpoorte since 2008. The participants will join together with international participants. For the lectures of metabolomics, 8-10 international guest lecturers will be invited. There is limitation of place for the students of Leiden University (ca. 10 places are available). The course will take place in Pieterskerkhof 6, Leiden (for lectures in the first week) and practice will be Sylvius building.